08:00
Accreditation
EDA Board private meeting
09:00
Welcome
Giovanna Iannantuoni (Italy), Arjen Slooter (The Netherlands), Giuseppe Bellelli (Italy)
09:10
Plenary Session 1
Lessons learned about COVID-19-related delirium
Chairs: Alessandro Morandi (Italy), Stefan Kreisel (Germany)
The impact of delirium with COVID-19: a pandemic within the pandemic?
Alessandra Marengoni (Italy)
The pathophysiology of delirium in SARS-CoV2 infection: something new?
Thomas Jackson (UK)
COVID-19 and delirium detection in practice: what lessons can we learn?
Alasdair MacLullich (UK)
Long-COVID: neurocognitive sequelae
Alessandro Padovani (Italy)
10:30
Coffee break
11:00
Keynote Lecture
Chair: Arjen Slooter (The Netherlands)
Exploring the relationship between delirium and Lewy body dementia
Annachiara Cagnin (Italy)
11:50
Plenary Session 2
Delirium pathophysiology
Chairs: Thomas Jackson (UK), Silvia Brunelli (Italy)
Cerebrospinal fluid biomarkers
Leiv Otto Watne (Norway)
Bioenergetic insufficiency as a mechanism for delirium development
Colm Cunningham (Ireland)
Functional connectivity biomarkers of delirium
Edwin van Dellen (The Netherlands)
12:50
Lunch Symposium
Sedation and delirium in intensive care unit
Chairs: Giuseppe Citerio (Italy), Stefano Romagnoli (Italy)
Drugs, strategies, and outcome
Federico Bilotta (Italy)
How to monitor sedation: from clinical to instrumental tools
Stefano Romagnoli (Italy)
Guidelines and recommendations: where are we?
Chiara Robba (Italy)
Discussion
13:45
Break
14:00
Parallel Session 3
Neurophysiological and fluid biomarkers in human delirium research
Chairs: Colm Cunningham (Ireland)
Clinical and Quantitative EEG changes as proxy measures of cytokine and brain network interactions in delirium
Robert Fleischmann (Germany)
Biomarker-guided pattern recognition – Can we track pathophysiological steps of delirium using body fluid biomarkers?
Johannes Ehler (Germany)
Electrophysiological markers for the prediction of post stroke delirium
Annerose Mengel (Germany)
Parallel Session 4
Delirium diagnosis
Chairs: Liz Sampson (UK), Alasdair MacLullich (Scotland)
Brief and reliable: update on the tools to detect delirium in ED
Wolfgang Hasemann (Switzerland)
Why delirium diagnosis is so hard to do in acute and surgical wards?
Suzanne Timmons (Ireland)
How much of a burden is the systematic screening of delirium in palliative care?
Meera Agar (Australia)
15:00
Coffee break
15:30
Parallel Session 5
Brain barriers and neuroinflammation during systemic inflammation
Chairs: Leiv Otto Watne (Norway), Silvia Brunelli (Italy)
Dynamic opening and closing of the choroid plexus vascular barrier during gut inflammation
Maria Rescigno (Italy)
Chemokines at brain barriers during systemic inflammation in mice and humans: associations with blood CSF barrier permeability and delirium
Paul Denver (Ireland)
New tools to study blood-brain barrier dysfunction in postoperative delirium
Niccolo Terrando (US)
Parallel Session 6
Oral presentations from submitted abstracts
Chairs: Christine Thomas (Germany), Emma Vardy (UK)
The role of preoperative anxiety in the development of postoperative delirium in older surgical patients: A systematic review and meta-analysis
Kelu Yang (Belgium)
Co-occurence of anaemia and delirium in older inpatients with hip fractures
Stefano Volpato (Italy)
Quality of life, cognitive and functional trajectories associated with postoperative delirium: a prospective cohort study in hip fracture patients with 1- and 3-month follow-up
Lucía Lozano Vicario (Spain)
Delirium-related Distress and Recovery Challenges Associated with COVID-19: an online survey
Heidi Lindroth (US)
Frailty and delirium: prevalence in a cohort of older patients undergoing elective neurosurgery
Valentina Stella (Italy)
Impairment of central language processing in critically-ill COVID-19 patients with delirium
William Buffieres (France)
Pre-critical illness frailty and delirium-coma free days in critically ill adults
Nathan Brummel (US)
Predictors of severe delirium in Covid-19: an observational study on 2288 consecutive hospitalized patients
Viviana Cristillo (Italy)
Delirium and dysphagia: is there an association in elderly patients admitted to a rehabilitation setting?
Eleonora Grossi (Italy)
17:00
E-POSTER SESSION
18:00
EDA General Assembly Meeting
08:15
Welcome to day 2 of EDA 2022
08:30
Parallel Session 1
Joint symposium EDA EuGMS
Chairs: Emma Cunningham (UK), Daniel Davis (UK)
Melatoninergic drugs and orexin inhibitors to prevent delirium
Carolina Lombardi (Italy)
Medications and delirium: a complex relationship
Antonio Cherubini (Italy)
Preventing delirium in cardiac and non-cardiac surgical patients
Christine Thomas (Germany)
Parallel Session 2
Delirium in ICU: new insights
Chairs: Timothy Girard (US), Simone Piva (Italy)
Sedation and pain management in ICU: this is the question
Nina Christine Andersen-Ranberg (Denmark)
Improving ICU patients’ environment to decrease the delirium burden
Alawi Lütz (Germany)
The future of delirium management in the ICU: new perspectives
Pratik Pandharipande (US)
10:00
Coffee break
10:20
Keynote Lecture
Chair: Giuseppe Bellelli (Italy)
The challenge of delirium and dementia follow-up in the community
Daniel Davis (UK)
11:10
Parallel Session 3
Pediatric management of delirium
Chairs: Andrea Biondi (Italy), Jacqueline Strik (Netherlands)
Guidelines on the detection and prevention of pediatric delirium
Heidi Smith (US)
Non-pharmacological interventions to prevent delirium in pediatric patients
Bronagh Blackwood (Ireland)
Parallel Session 4
Postoperative delirium
Chairs: Simone Piva (Italy), Cynthia Olotu (Germany)
Risk factor of postoperative delirium
Maria Wittmann (Germany)
Sleep disturbances and postoperative delirium outside the ICU
Federico Bilotta (Italy)
Parallel Session 5
Oral presentations from submitted abstracts
Chairs: Paolo Mazzola (Italy), Bjorn Erik Neerland (Norway)
Postoperative delirium is associated with grey matter brain volume loss
Bob Walraad (The Netherlands)
Dysregulation of cerebral autoregulation as a pathophysiological mechanism underlying delirium: A precision medicine approach to ICU delirium
Jasmine Khan (Canada)
Assessing recovery from delirium in older hospitalised patients: validation of the 4AT
Haruno McCartney (UK)
Targeted metabolomics of the cerebrospinal fluid suggests impaired glucose utilization in the brain in delirium following hip fracture
Irit Titlestad (Norway)
Randomised double-blind, placebo-controlled phase III trial of oral melatonin for the prevention of delirium in hospital in people with advanced cancer
Meera Agar (Australia)
Eight year follow-up of an observational Cohort of postoperative delirium in an older elective arthroplasty population – preliminary cognitive outcomes
Aoife Sweeney (UK)
12:30
Light lunch
13:30
Parallel Session 6
Delirium in non-hospital care settings
Chairs: Wolfgang Hasemann (Switzerland)
Diagnosing delirium in the community
Maria Krogseth (Norway)
Delirium management in rehabilitation
Neus Gual (Spain)
Delirium superimposed on dementia in non-hospital care settings
Shibley Rahman (UK)
Parallel Session 7
Shaping the next step of research and education on delirium: challenges and opportunities
Chairs: James Rudolph (US), Birgitta Olofsson (Sweden)
New perspectives in delirium research
Gideon Caplan (Australia)
Multimodal prehabilitation and delirium prevention
Stefan Kreisel (Germany)
Teaching delirium at medical schools: challenges and opportunities
Andrew Teodorczuk (Australia)
14:30
E-POSTER SESSION
15:30
Announcement of EDA 2023, ADS 2023, ADA 2023
Maeve Leonard Award
Best Oral Communication Award
Best Poster Award
Closing remarks